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Combined effect of anemia and chronic rhinitis on hearing loss in Korean adults: a nationwide observational study
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Yeong Jun Ju, Woorim Kim, Jina Han, Soon Young Lee
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Epidemiol Health. 2024;e2024063. Published online July 15, 2024
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DOI: https://doi.org/10.4178/epih.e2024063
[Accepted]
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Abstract
OBJECTIVES Studies have suggested an association between hearing loss and anemia. Hearing loss has also been linked to rhinitis, which is characterized by inflammation of the nasal mucous membranes and sinus mucosa. Few studies have concurrently explored the relationships between hearing loss, anemia, and rhinitis. This study was conducted to investigate the association between hearing loss and anemia and to further analyze the potential role of rhinitis in this relationship.
METHODS Data were collected from the 2020 Korea National Health and Nutrition Examination Survey. Hearing loss was measured with an audiometer in a soundproof booth and was defined as at least moderate impairment (as indicated by a pure-tone average of ≥41 dB in the better-hearing ear). The association between hearing loss and anemia was analyzed using multivariable logistic regression. The combined effect of anemia and rhinitis on hearing loss was assessed with an interaction term.
RESULTS Among the 2,772 participants, 477 (17.2%) exhibited hearing loss. Participants with anemia were more likely to experience hearing loss than those without anemia (odds ratio [OR], 1.58; 95% confidence interval [CI], 1.07 to 2.33). Furthermore, the odds of hearing loss were greater in participants with both anemia and rhinitis (OR, 3.79; 95% CI, 1.93 to 7.43) relative to those without either condition.
CONCLUSIONS Anemia was associated with hearing loss in individuals aged 40 years and older. Based on the analysis of combined effects, participants with anemia and chronic rhinitis were more likely to experience hearing loss than individuals without these conditions.
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Summary
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Physical activity, sedentary behavior, and cardiovascular disease risk in Korea: a trajectory analysis
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Jina Han, Yeong Jun Ju, Soon Young Lee
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Epidemiol Health. 2023;45:e2023028. Published online February 22, 2023
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DOI: https://doi.org/10.4178/epih.e2023028
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OBJECTIVES To identify the distinct trajectories of sedentary behavior (SB) and explore whether reduced cardiovascular disease (CVD) risk was associated with a distinct trajectory of physical activity (PA).
METHODS We analyzed data from 6,425 people who participated in the Korean Health Panel Survey over a period of 10 years. The participants’ self-reported SB and PA were assessed annually, and trajectory groups were identified using a group-based trajectory model for longitudinal data analysis. Logistic regression analysis was performed to assess the association between CVD risk (10-year cumulative incidence) and the trajectories of SB and PA. The adjusted variables included socio-demographic factors, the predisposing diseases of CVD, and baseline health behaviors.
RESULTS Trajectory analysis identified 4 SB trajectory groups: SB group 1 (low and slightly increasing trend, 53.1%), SB group 2 (high and rapidly decreasing trend, 14.7%), SB group 3 (high and slightly decreasing trend, 9.9%), and SB group 4 (low and rapidly increasing trend, 22.2%). The 3 PA trajectory groups were PA group 1 (moderate and slightly decreasing trend, 32.1%), PA group 2 (low and slightly decreasing trend, 57.3%), and PA group 3 (maintained inactivity, 10.7%). By the 10-year follow-up, 577 cases of incident CVD had occurred. We also noted a 50% reduction in the risk of CVD when SB group 4 was accompanied by PA group 1 (odds ratio, 0.50; 95% confidence interval, 0.28 to 0.90).
CONCLUSIONS Despite increased time spent in SB, maintaining PA about 2 days to 3 days per week reduced the occurrence of CVD.
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Summary
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Citations
Citations to this article as recorded by
- Effects of physical activity and sedentary behaviors on cardiovascular disease and the risk of all-cause mortality in overweight or obese middle-aged and older adults
Yongqiang Zhang, Xia Liu Frontiers in Public Health.2024;[Epub] CrossRef - Modulating the Expression of Exercise-induced lncRNAs: Implications for Cardiovascular Disease Progression
Li-Hua Yu, Ge-Lin Zhang Journal of Cardiovascular Translational Research.2024;[Epub] CrossRef
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Does having various types of fear related to COVID-19 disrupt individuals’ daily life?: Findings from a nationwide survey in Korea
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Woorim Kim, Yeong Jun Ju, Soon Young Lee
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Epidemiol Health. 2022;44:e2022004. Published online January 3, 2022
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DOI: https://doi.org/10.4178/epih.e2022004
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11,256
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OBJECTIVES Unexpected changes in daily routines caused by the coronavirus disease 2019 (COVID-19) pandemic may affect psychological health. This study investigated the association between various types of COVID-19-related fear and the subjective level of disturbance in daily activities experienced by individuals.
METHODS This cross-sectional study used the Korea Community Health Survey conducted from August through November 2020. COVID-19-related fear included fear of infection, death, public criticism, family members getting infected, and economic loss. The subjective level of disruption in daily activities was measured using a 0-100 numeric rating scale developed by the Korea Disease Control and Prevention Agency. Multivariable linear regression was used to analyze the associations between the independent and dependent variables. A subgroup analysis was performed based on income level.
RESULTS Participants who reported fear of infection (β=-3.37, p<0.001), death (β=-0.33, p=0.030), public criticism (β=-1.63, p<0.001), a family member getting infected (β=-1.03, p<0.001), and economic loss (β=-3.52, p<0.001) experienced more disturbances in daily activities. The magnitude of this association was most significant in the lowest-income group.
CONCLUSIONS Individuals reporting COVID-19-related fear experienced higher levels of subjective disruption in daily activities.
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Summary
Korean summary
이 연구는 COVID-19 팬데믹과 관련된 심리적염려가 일상생활 활동에 부정적인 영향을 줄 수 있음을 관찰하였다.
COVID-19 감염으로 인한 감염, 사망, 대중의 비판, 가족 중 건강취약자의 감염, 경제적 손실에 대해 염려하는 사람은 그렇지 않은 사람에 비해 일상생활에 더 부정적인 영향을 받고 있는 것으로 관찰되었다.
특히 다양한 유형의 감염염려를 동시에 경험하고 있을수록 일상생활 지장 정도가 더 증가하는 경향이 관찰되었으며 소득수준이 낮을수록 부정적인 영향정도가 더 두드러졌다.
Key Message
Our results revealed that fear related to the COVID-19 pandemic was associated with increased levels of subjective disruptions in daily activities.
Compared to individuals without fear, those with fears of COVID-19 infection, dying from infection, public criticism, a family member getting infected, and economic loss reported higher levels of disruption in daily activities.
Those who reported fear of COVID-19 infection and economic loss due to infection had particularly higher levels of disturbances.
Considering the various types of fear concurrently, the level of disruption experienced tended to increase with the number of reported fears.
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Citations
Citations to this article as recorded by
- Is fear of COVID-19 higher in individuals residing in more deprived areas? A nationwide study
Woorim Kim, Soon Young Lee, Yeong Jun Ju Journal of Public Health.2023; 45(2): 402. CrossRef - Association Between Changes in Family Life Due to COVID-19 and Depressive Mood and Stress Perception
Min-Su Kim, Mi Ah Han, Jong Park, So Yeon Ryu Asia Pacific Journal of Public Health.2023; 35(1): 14. CrossRef - Public perception of the appropriateness of COVID-19 management strategies and level of disturbances in daily activities: A focus on educational level
Yeong Jun Ju, Woorim Kim, Soon Young Lee, Jordi Gumà PLOS ONE.2023; 18(6): e0287143. CrossRef
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A comprehensive study of deaths due to exposure to humidifier disinfectant in Korea: focusing on medical records, assessment of exposure to humidifier disinfectants, and causes of death
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Yeong Jun Ju, Seungho Lee, Seungsoo Sheen, Dong-Woo Choi, Jong-Han Leem, Soon Young Lee
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Epidemiol Health. 2021;43:e2021091. Published online November 1, 2021
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DOI: https://doi.org/10.4178/epih.e2021091
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11,389
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PDFSupplementary Material
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Abstract
OBJECTIVES We aimed to determine the characteristics of the deceased victims of deaths caused by exposure to humidifier disinfectants, and present the distribution of the victims’ data submitted for damage application, demographic characteristics, imaging findings, characteristics of humidifier disinfectant exposure, and distribution of the causes of death.
METHODS An integrated database of victims was established using the medical records data of 1,413 victims submitted during the application for death damage caused by exposure to humidifier disinfectants, and the demographic characteristics, medical records, imaging findings, exposure characteristics, and cause of death were examined.
RESULTS The average numbers of data submissions of each applicant for death damage were 3.0 medical use records. A total of 608 (43.0%) victims had more than one finding of acute, subacute, or chronic interstitial lung diseases. The average daily and cumulative use times of the victims were 14.40 and 24,645.81 hours, respectively, indicating greater exposure in this group than in the survivors. The humidifier disinfectants’ components comprised polyhexamethylene guanidine (72.8%), chloromethylisothiazolinone/methylisothiazolinone (10.5%), other components (15.0%), and oligo-[2-(2-ethoxy)-ethoxyethyl] guanidine chloride (1.5%). The components’ distribution was 67.8% for single-component use, which was higher than that in the survivors (59.8%). The distribution of the causes of death were: respiratory diseases (54.4%), neoplasms (16.8%), and circulatory diseases (6.3%). Other interstitial lung diseases (65.5%) were the most common cause of death among those who died due to respiratory diseases.
CONCLUSIONS Careful discussions of appropriate remedies should be conducted based on a comprehensive understanding of the characteristics of the deceased victims, considering their specificities and limitations.
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Summary
Korean summary
가습기 살균제 사망 피해 신청자 들 중 건강피해를 인정받지 못한 신청자들이 여전히 많이 남아있으며 (약 40%), 피해판정의 복잡성과 다양한 이슈들이 산적해 있어 사망 피해 신청자들의 적정 구제를 위해 종합적인 특성파악을 바탕으로 세심한 관점에서의 검토가 필요하다. 특히, 가습기 살균제 사망 피해 신청자의 특수성과 피해구제의 제한점을 고려하여야 하며, 기계적인 건강피해 판정을 지양하고 사망 피해 신청자 중심의 세밀한 특성 파악을 바탕으로 다양한 전문가집단이 참여하는 종합적인 논의를 통해 적정구제를 이루어 나가야 함을 제안한다.
Key Message
Careful discussions of appropriate remedies should be conducted based on a comprehensive understanding of the characteristics of the deceased victims, considering their specificities and limitations.
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Citations
Citations to this article as recorded by
- Polyhexamethylene Guanidine Phosphate Enhanced Procoagulant Activity through Oxidative-Stress-Mediated Phosphatidylserine Exposure in Platelets
Ju Hee Choi, Keunyoung Kim Toxics.2024; 12(1): 50. CrossRef - Next generation risk assessment of biocides (PHMG-p and CMIT/MIT)-induced pulmonary fibrosis using adverse outcome pathway-based transcriptome analysis
Jun Woo Kim, Hyung Sik Kim, Ha Ryong Kim, Kyu Hyuck Chung Journal of Hazardous Materials.2024; 476: 134986. CrossRef - Metabolite analysis of 14C-labeled chloromethylisothiazolinone/methylisothiazolinone for toxicological consideration of inhaled isothiazolinone biocides in lungs
Jung Eun Park, Seung-Hun Ryu, Satoshi Ito, Hyunil Shin, Young-Hee Kim, Jongho Jeon Chemosphere.2024; 362: 142666. CrossRef - Toxicity and Safety Analysis of Polyhexamethylene Guanidine: A Comprehensive Systematic Review
Ivan Ivanov, Daria Kirillova, Kenes Erimbetov, Denis Shatalov Sciences of Pharmacy.2024; 3(3): 153. CrossRef - Gene expression related to lung cancer altered by PHMG-p treatment in PBTE cells
Yoon Hee Park, Sang Hoon Jeong, Hyejin Lee, Cherry Kim, Yoon Jeong Nam, Ja Young Kang, Jin Young Choi, Yu-Seon Lee, Su A. Park, Jaeyoung Kim, Eun-Kee Park, Yong-Wook Baek, Hong Lee, Ju-Han Lee Molecular & Cellular Toxicology.2023; 19(1): 205. CrossRef - Health Effects Associated With Humidifier Disinfectant Use: A Systematic Review for Exploration
Ji-Hun Song, Joonho Ahn, Min Young Park, Jaeyoung Park, Yu Min Lee, Jun-Pyo Myong, Jung-Wan Koo, Jongin Lee Journal of Korean Medical Science.2022;[Epub] CrossRef
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