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Most-read articles are from the articles published in 2021 during the last three month.

Original Article
Risk of cancer, cardiovascular disease, thromboembolism, and mortality in patients with rheumatoid arthritis receiving Janus kinase inhibitors: a real-world retrospective observational study using Korean health insurance data
Hong Ki Min, Hyeongsu Kim, Ho Jin Jeong, Se Hee Kim, Hae-Rim Kim, Sang-Heon Lee, KunSei Lee, Soon-Ae Shin, Jong Heon Park
Epidemiol Health. 2023;45:e2023045.   Published online April 15, 2023
DOI: https://doi.org/10.4178/epih.e2023045
  • 2,564 View
  • 225 Download
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
This study investigated whether Janus kinase inhibitors (JAKis) raise the risk of cardiovascular disease (CVD), venous thromboembolism (VTE), and cancer in patients with rheumatoid arthritis (RA).
METHODS
We conducted a real-world retrospective observational study using data obtained from the Korean National Health Insurance Service database. Two data sets were analyzed: tumor necrosis factor inhibitor (TNFi)/JAKi-naive RA patients (set 1) and all RA patients who used TNFis or JAKis (set 2). The incidence rate ratios (IRRs) and hazard ratios (HRs) for acute myocardial infarction (AMI), stroke, cardiovascular (CV)-related mortality, major adverse cardiovascular events (MACE), VTE, arterial thromboembolism (ATE), cancer, and all-cause mortality were compared between the JAKi and TNFi groups.
RESULTS
Set 1 included 1,596 RA patients (JAKi group: 645; TNFi group: 951), and set 2 included 11,765 RA patients (JAKi group: 2,498; TNFi group: 9,267). No adverse events (AEs) showed significantly higher IRRs in the JAKi groups than in the TNFi groups of sets 1 and 2. The HRs for MACE in the JAKi groups of sets 1 and 2 were 0.59 (95% confidence [CI], 0.35 to 0.99) and 0.80 (95% CI, 0.67 to 0.97), respectively. The JAKi group of set 2 showed a significantly higher risk of all-cause mortality (HR, 1.71; 95% CI, 1.32 to 2.20), but the other AEs did not demonstrate increased risks in the JAKi groups.
CONCLUSIONS
In this study, JAKis did not increase the risk of AMI, stroke, CV-related mortality, MACE, VTE, ATE, or cancer in Korean RA patients relative to TNFis.
Summary
Korean summary
1. 한국인 류마티스관절염 환자를 대상으로 한 실제임상자료 결과, JAK 억제제가 종양괴사인자 억제제에 비해 심혈관질환, 혈전증, 암 등의 심각한 부작용을 증가시키지는 않았다. 2. 본 연구를 토대로 한국인 대상자에서 JAK 억제제가 심혈관질환 등의 심각한 부작용을 증가시키는지에 대한 재평가가 필요하다.
Key Message
1. The real word-data based results showed that risks of MACE, thromboembolism, and cancers were not increased in Korean RA patients with JAK inhibitor when compared to Korean RA patients with TNF inhibitors. 2. Therefore, the risk of serious adverse events of JAK inhibitors in Korean population should be reconsidered and reassessed before adding black box warning of JAK inhibitors.
Methods
Korea National Health and Nutrition Examination Survey, 20th anniversary: accomplishments and future directions
Kyungwon Oh, Yoonjung Kim, Sanghui Kweon, Soyeon Kim, Sungha Yun, Suyeon Park, Yeon-Kyeng Lee, Youngtaek Kim, Ok Park, Eun Kyeong Jeong
Epidemiol Health. 2021;43:e2021025.   Published online April 19, 2021
DOI: https://doi.org/10.4178/epih.e2021025
  • 15,681 View
  • 538 Download
  • 40 Citations
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
The Korea National Health and Nutrition Examination Survey (KNHANES) was initiated in 1998 to provide evidence for the development and evaluation of health policies and programs. The Korea Disease Control and Prevention Agency is responsible for the KNHANES and has conducted it as a series of surveys. Over the past 20 years, efforts to produce accurate, timely, and nationwide health statistics have been refined by establishing a continuous annual survey system with full-time field staff, incrementally expanding survey components, collaborating with relevant academic societies for quality control, and revising the survey methods. Additionally, the utility of the collected data was increased by linking the KNHANES data with related data from other government agencies or institutions and making the overall data publicly available on the official website of KNHANES (https://knhanes.kdca.go.kr). Additional long-term plans are being developed, including plans to continue producing nationwide health indicators and invigorating the utilization of the KNHANES data.
Summary
Korean summary
국민건강영양조사는 국민건강증진법제16조에 근거하여 1998년부터 우리 국민의 건강수준, 건강행태, 식품 및 영양소 섭취 실태에 대한 국가단위 통계를 산출하는 조사사업이다. 본 연구에서는 건강지표 생산 확대, 조사 자료 활용도 향상 등 20년간의 성과를 요약하고 사회환경과 조사여건 변화를 반영한 건강통계 생산의 발전 방안을 제시하였다.
Key Message
The Korea National Health and Nutrition Examination Survey (KNHANES) is an ongoing surveillance system that was initiated in 1998 based on Ar¬ticle 16 of the National Health Promotion Act to produce nationwide statistics regarding the health status, health behaviors, and food and nutrient consumption of the Korean population. In this study, the 20-year accomplishments of the KNHANES including vigorous production of health indicators and improvement of data utilization are summarized, and future plans are presented to improve the health statistics to reflect changes in the social and survey environments.

Citations

Citations to this article as recorded by  
  • Association between Obstructive Sleep Apnea and Chronic Kidney Disease According to Sex, Long Working Hours: The Korean National Health and Nutrition Examination Survey (2019–2020)
    Sung-Min Jung, Mee-Ri Lee
    Life.2023; 13(8): 1625.     CrossRef
  • Impact of the COVID-19 Pandemic on Gender Differences in Depression Based on National Representative Data
    Hyunsuk Jeong, Hyeon Woo Yim, Seung-Yup Lee, Da Young Jung
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • Identifying the Group Vulnerable to Unmet Medical Needs Due to Food Security: According to Children in the Household
    Min-Soo Kim, Hyeon-Ji Lee, Jae-Hyun Kim
    Healthcare.2023; 11(3): 423.     CrossRef
  • Food Insecurity Is Associated with Dietary Consumption during the COVID-19 Pandemic: Data from the Korea National Health and Nutrition Examination Survey 2019–2020
    Jeong-Hwa Choi
    Nutrients.2023; 15(3): 772.     CrossRef
  • Metabolically unhealthy phenotype in adults with normal weight: Is cardiometabolic health worse off when compared to adults with obesity?
    Myong-Won Seo, Joon Young Kim
    Obesity Research & Clinical Practice.2023; 17(2): 116.     CrossRef
  • Sleep duration, weekend catch-up sleep, and risk of obstructive sleep apnea in relation to handgrip strength
    Kayoung Lee
    Archives of Gerontology and Geriatrics.2023; 110: 104987.     CrossRef
  • Prevalence and trends in obesity and severe obesity in Korean children and adolescents, 2007–2020: A population‐based study
    Hong Kyu Park, Ji‐Young Seo, Hae Woon Jung, Jung Sub Lim
    Pediatrics International.2023;[Epub]     CrossRef
  • Evaluation of weekend catch-up sleep and weekday sleep duration in relation to metabolic syndrome in Korean adults
    Kayoung Lee
    Sleep and Breathing.2023;[Epub]     CrossRef
  • Self-Reported Reasons for Activity Limitations According to Age and Sex in Community-Dwelling Stroke Survivors
    Young-Ah Choi, Yeo Hyung Kim
    Healthcare.2023; 11(10): 1420.     CrossRef
  • Relationships of neck circumference and abdominal obesity with insulin resistance considering relative handgrip strength in middle-aged and older individuals
    Kayoung Lee
    Archives of Gerontology and Geriatrics.2023; 114: 105097.     CrossRef
  • Temporal Trends of the Prevalence of Abdominal Obesity and Metabolic Syndrome in Korean Children and Adolescents between 2007 and 2020
    Jieun Lee, Sung-Chan Kang, Obin Kwon, Seung-sik Hwang, Jin Soo Moon, Hyun Wook Chae, Jaehyun Kim
    Journal of Obesity & Metabolic Syndrome.2023; 32(2): 170.     CrossRef
  • National trends in influenza vaccination coverage rates in South Korea between 2007-2020, including the COVID-19 pandemic: a longitudinal nationwide serial study
    Hyeon Jin Kim, Hyeowon Park, Dong Keon Yon, Masoud Rahmati
    Life Cycle.2023;[Epub]     CrossRef
  • Sedentary Behavior and Physical Activity of Community-Dwelling Korean Breast Cancer Survivors: A Nationwide Study
    Jung Soo Lee, Mina Park, Yeo Hyung Kim
    Healthcare.2023; 11(13): 1974.     CrossRef
  • Association between breastfeeding and periodontitis in Korean women using Korea National Health and Nutrition Examination Survey (KNHANES): a cross-sectional study
    Zi-Lan Wang, Seung-Hee Ryu, Kwang-Hak Bae, Seon-Jip Kim, Hyun-Jae Cho
    BMC Oral Health.2023;[Epub]     CrossRef
  • Korea hypertension fact sheet 2022: analysis of nationwide population-based data with a special focus on hypertension in the elderly
    Hyeon Chang Kim, Hokyou Lee, Hyeok-Hee Lee, Gabin Lee, Eunji Kim, Moses Song, Jenny Moon, Yeeun Seo
    Clinical Hypertension.2023;[Epub]     CrossRef
  • Sex-Specific Trends in the Prevalence of Hypertension and the Number of People With Hypertension: Analysis of the Korea National Health and Nutrition Examination Survey (KNHANES) 1998–2018
    Eunsun Seo, Sunjae Jung, Hokyou Lee, Hyeon Chang Kim
    Korean Circulation Journal.2022; 52(5): 382.     CrossRef
  • Inverse Association of Serum Folate Level with Metabolic Syndrome and Its Components in Korean Premenopausal Women: Findings of the 2016–2018 Korean National Health Nutrition Examination Survey
    Ye-Seul Koo, Yong-Jae Lee, Jae-Min Park
    Nutrients.2022; 14(4): 880.     CrossRef
  • Lower Dietary Calcium Intake is Associated with a Higher Risk of Mortality in Korean Adults
    Jin Young Yoo, Hyun Jeong Cho, Jung Eun Lee
    Journal of the Academy of Nutrition and Dietetics.2022; 122(11): 2072.     CrossRef
  • Association between exposure to fine particulate matter and kidney function: Results from the Korea National Health and Nutrition Examination Survey
    Jongmin Oh, Shinhee Ye, Duk-Hee Kang, Eunhee Ha
    Environmental Research.2022; 212: 113080.     CrossRef
  • Cardiovascular Implications of the 2021 KDIGO Blood Pressure Guideline for Adults With Chronic Kidney Disease
    Hyeok-Hee Lee, Hokyou Lee, Raymond R. Townsend, Dong-Wook Kim, Sungha Park, Hyeon Chang Kim
    Journal of the American College of Cardiology.2022; 79(17): 1675.     CrossRef
  • The Korea National Health and Nutrition Examination Survey data linked Cause of Death data
    Sungha Yun, Kyungwon Oh
    Epidemiology and Health.2022; 44: e2022021.     CrossRef
  • Obesity, hypertension, diabetes mellitus, and hypercholesterolemia in Korean adults before and during the COVID-19 pandemic: a special report of the 2020 Korea National Health and Nutrition Examination Survey
    Ga Bin Lee, Yoonjung Kim, Suyeon Park, Hyeon Chang Kim, Kyungwon Oh
    Epidemiology and Health.2022; 44: e2022041.     CrossRef
  • Mental health of Korean adults before and during the COVID-19 pandemic: a special report of the 2020 Korea National Health and Nutrition Examination Survey
    Hyunsuk Jeong, Suyeon Park, Jihee Kim, Kyungwon Oh, Hyeon Woo Yim
    Epidemiology and Health.2022; 44: e2022042.     CrossRef
  • Diabetes Fact Sheet in Korea 2021
    Jae Hyun Bae, Kyung-Do Han, Seung-Hyun Ko, Ye Seul Yang, Jong Han Choi, Kyung Mook Choi, Hyuk-Sang Kwon, Kyu Chang Won
    Diabetes & Metabolism Journal.2022; 46(3): 417.     CrossRef
  • Serum folate levels and hypertension
    Yoonkyung Lee, Sangshin Park
    Scientific Reports.2022;[Epub]     CrossRef
  • The Relationship between Lipid Accumulation Product, Insulin Resistance and Obesity in Korean Adults
    Hyun Yoon
    Korean Journal of Clinical Laboratory Science.2022; 54(2): 149.     CrossRef
  • Relationship between Anemia and Falls among Postmenopausal Women in Korea
    Yunmi Kim, Jiyun Kim
    International Journal of Environmental Research and Public Health.2022; 19(14): 8242.     CrossRef
  • Smoking in the workplace: A study of female call center employees in South Korea
    Hyunjin Oh, Sunjoo Boo, Petri Böckerman
    PLOS ONE.2022; 17(7): e0267685.     CrossRef
  • Alterations in Glomerular Filtration Rates Using Different Algorithms in the Korean Population Visiting Local Clinics and Hospitals
    Rihwa Choi, Sang Gon Lee, Eun Hee Lee
    Journal of Clinical Medicine.2022; 11(18): 5339.     CrossRef
  • Prevalence Trends of Metabolic Syndrome among Korean Children and Adolescents from a Population-Based Cross-Sectional Survey
    Ji Hyun Kim, Jung Sub Lim
    Life.2022; 12(9): 1404.     CrossRef
  • The Association of Mercury and ALT with Obesity in Korean Adults: Using Data from the Korea National Health and Nutrition Examination Survey for 11 Years (KNHANES 2005, 2008~2017)
    Sang Shin Pyo
    Korean Journal of Clinical Laboratory Science.2022; 54(3): 192.     CrossRef
  • Low relative hand grip strength is associated with a higher risk for diabetes and impaired fasting glucose among the Korean population
    Min Jin Lee, Ah Reum Khang, Dongwon Yi, Yang Ho Kang, Giacomo Pucci
    PLOS ONE.2022; 17(10): e0275746.     CrossRef
  • Menstrual and Reproductive Factors for Gastric Cancer in Postmenopausal Women: The 2007–2020 Korea National Health and Nutrition Examination Survey
    Heekyoung Song, Jung Yoon Park, Ju Myung Song, Youngjae Yoon, Yong-Wook Kim
    International Journal of Environmental Research and Public Health.2022; 19(21): 14468.     CrossRef
  • Prevalence and management of hypertension in Korean adults
    Hyeon Chang Kim
    Journal of the Korean Medical Association.2022; 65(10): 633.     CrossRef
  • One-year prevalence and clinical characteristics in chronic dizziness: The 2019–2020 Korean National Health and Nutrition Examination Survey
    Eun Ji Kim, Hee-Jung Song, Hak In Lee, Eunjin Kwon, Seong-Hae Jeong
    Frontiers in Neurology.2022;[Epub]     CrossRef
  • Spousal concordance of ideal cardiovascular health metrics: findings from the 2014–2019 Korea National Health and Nutrition Examination Survey
    Manh Thang Hoang, Hokyou Lee, Hyeon Chang Kim
    Clinical Hypertension.2022;[Epub]     CrossRef
  • Changes in the prevalence of metabolic syndrome in Korean adults after the COVID-19 outbreak
    Ji-Young Kwon, Sang-Wook Song
    Epidemiology and Health.2022; 44: e2022101.     CrossRef
  • Item non-response imputation in the Korea National Health and Nutrition Examination Survey
    Serhim Son, Hyemi Moon, Hyonggin An
    Epidemiology and Health.2022; 44: e2022096.     CrossRef
  • The Interaction of High Sensitivity C-Reactive Protein and Uric Acid on Obesity in Koreans: Based on the Seventh Korea National Health and Nutrition Examination Survey (KNHANES VII, 2016∼2018)
    Sang Shin Pyo
    Korean Journal of Clinical Laboratory Science.2021; 53(4): 342.     CrossRef
  • Non-cancer disease prevalence and association with occupational radiation exposure among Korean radiation workers
    Soojin Park, Dal Nim Lee, Young Woo Jin, Eun Shil Cha, Won-Il Jang, Sunhoo Park, Songwon Seo
    Scientific Reports.2021;[Epub]     CrossRef
Special Article
The Korea National Disability Registration System
Miso Kim, Wonyoung Jung, So Young Kim, Jong Hyock Park, Dong Wook Shin
Epidemiol Health. 2023;45:e2023053.   Published online May 11, 2023
DOI: https://doi.org/10.4178/epih.e2023053
  • 1,918 View
  • 149 Download
  • 1 Citations
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
The Korea National Disability Registration System (KNDRS) was established in 1989 to provide social welfare benefits based on predefined criteria for disability registration and an objective medical assessment using a disability grading system. Disability registration requires (1) a medical examination by a qualified specialist physician and (2) a medical advisory meeting to review the degree of disability. Medical institutions and specialists for the diagnosis of disabilities are legally stipulated, and medical records for a specified period are required to support the diagnosis. The number of disability types has gradually expanded, and 15 disability types have been legally defined. As of 2021, 2.645 million people were registered as disabled, accounting for approximately 5.1% of the total population. Among the 15 disability types, disabilities of the extremities account for the largest proportion (45.1%). Previous studies have investigated the epidemiology of disabilities using data from the KNDRS, combined predominantly with data from the National Health Insurance Research Database (NHIRD). Korea has a mandatory public health insurance system that covers the entire Korean population, and the National Health Insurance Services manages all eligibility information, including disability types and severity ratings. In short, the KNDRS-NHIRD is a significant data resource for research on the epidemiology of disabilities.
Summary
Korean summary
한국에서는 장애의 유형과 장애 유형별 장애정도를 장애인 복지법에서 규정하고 있다. 우리는 한국의 장애등록제도의 역사와 장애등록절차 그리고 장애유형별 통계 현황에 대해서 다루고자 한다.
Key Message
In Korea, the types and severity levels of disabilities are legally defined by the Korea National Disability Registration System (KNDRS). We address the history of the KNDRS, disability registration procedures, and current statistics.

Citations

Citations to this article as recorded by  
  • Increased risk of Parkinson's disease amongst patients with age‐related macular degeneration and visual disability: A nationwide cohort study
    Je Moon Yoon, Dong Hui Lim, Jinyoung Youn, Kyungdo Han, Bong Sung Kim, Wonyoung Jung, Yohwan Yeo, Dong Wook Shin, Don‐Il Ham
    European Journal of Neurology.2023; 30(9): 2641.     CrossRef
COVID-19: Original Article
The role of vitamin D deficiency on COVID-19: a systematic review and meta-analysis of observational studies
Mehmet Onur Kaya, Esra Pamukçu, Burkay Yakar
Epidemiol Health. 2021;43:e2021074.   Published online September 23, 2021
DOI: https://doi.org/10.4178/epih.e2021074
  • 13,169 View
  • 607 Download
  • 33 Citations
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
Although vaccination has started, coronavirus disease 2019 (COVID-19) poses a continuing threat to public health. Therefore, in addition to vaccination, the use of supplements to support the immune system may be important. The purpose of this study was to synthesize evidence on the possible effect of low serum vitamin D levels (25[OH]D<20 ng/mL or 50 nmol/L) on COVID-19 infection and outcomes.
METHODS
We searched Google Scholar, PubMed, Scopus, Web of Science, and ScienceDirect without any language restrictions for articles published between January 1 and December 15, 2020. We performed 3 meta-analyses (called vitamin D and COVID-19 infection meta-analysis [D-CIMA], vitamin D and COVID-19 severity meta-analysis [D-CSMA], and vitamin D and COV ID-19 mortality meta-analysis [D-CMMA] for COVID-19 infection, severity, and mortality, respectively) to combine odds ratio values according to laboratory measurement units for vitamin D and the measured serum 25(OH)D level.
RESULTS
Twenty-one eligible studies were found to be relevant to the relationship between vitamin D and COVID-19 infection/outcomes (n=205,869). The D-CIMA meta-analysis showed that individuals with low serum vitamin D levels were 1.64 times (95% confidence interval [CI], 1.32 to 2.04; p<0.001) more likely to contract COVID-19. The D-CSMA meta-analysis showed that people with serum 25(OH)D levels below 20 ng/mL or 50 nmol/L were 2.42 times (95% CI, 1.13 to 5.18; p=0.022) more likely to have severe COVID-19. The D-CMMA meta-analysis showed that low vitamin D levels had no effect on COVID-19 mortality (OR, 1.64; 95% CI, 0.53 to 5.06, p=0.390).
CONCLUSIONS
According to our results, vitamin D deficiency may increase the risk of COVID-19 infection and the likelihood of severe disease. Therefore, we recommend vitamin D supplementation to prevent COVID-19 and its negative outcomes.
Summary
Key Message
Although vaccination has started, it seems that Covid-19 will continue to threaten public health for a long time. In addition to the vaccine, the use of supplements to support the immune system may also be important. The purpose of this study is to indicate the possible effect of low serum vitamin D (25(OH)D<20 ng/mL or 50nmol/L) on the Covid-19 infection and outcomes. According to our remarkable results, vitamin D deficiency increases the risk of Covid-19 infection and the potential for the severity of the disease. Therefore, vitamin D supplements should be added to prevention and treatment protocols for Covid-19 disease.

Citations

Citations to this article as recorded by  
  • Vitamin D in the prevention or treatment of COVID-19
    Adrian R. Martineau
    Proceedings of the Nutrition Society.2023; 82(2): 200.     CrossRef
  • 100 years of vitamin D. The impact of vitamin D level in the time of COVID-19 pandemic
    K. A. Golovatyuk, A. A. Mikhailova, D. I. Lagutina, A. T. Chernikova, T. L. Karonova
    Russian Journal for Personalized Medicine.2023; 2(6): 33.     CrossRef
  • Vitamin D3 and COVID-19 Outcomes: An Umbrella Review of Systematic Reviews and Meta-Analyses
    Fausto Petrelli, Simone Oldani, Karen Borgonovo, Mary Cabiddu, Giuseppina Dognini, Mara Ghilardi, Maria Chiara Parati, Daniela Petro’, Lorenzo Dottorini, Carmen Rea, Veronica Lonati, Andrea Luciani, Antonio Ghidini
    Antioxidants.2023; 12(2): 247.     CrossRef
  • Genetic Variations of the Vitamin D Metabolic Pathway and COVID-19 Susceptibility and Severity: Current Understanding and Existing Evidence
    Nipith Charoenngam, Aunchalee Jaroenlapnopparat, Sofia K. Mettler, Ashna Grover
    Biomedicines.2023; 11(2): 400.     CrossRef
  • MC-Au/MSS-Z8 porous network assisted advanced electrochemical immunosensing of 25-hydroxyvitamin D3
    Amandeep Kaur, Lavisha, Ganga Ram Chaudhary, Nirmal Prabhakar
    Talanta.2023; 257: 124376.     CrossRef
  • Nutritional deficiencies that may predispose to long COVID
    John V. Schloss
    Inflammopharmacology.2023; 31(2): 573.     CrossRef
  • Changes in Food Consumption Trends among American Adults since the COVID-19 Pandemic
    Lillie Monroe-Lord, Elgloria Harrison, Azam Ardakani, Xuejling Duan, Lily Spechler, Tia D. Jeffery, Phronie Jackson
    Nutrients.2023; 15(7): 1769.     CrossRef
  • The Role of Diet and Specific Nutrients during the COVID-19 Pandemic: What Have We Learned over the Last Three Years?
    Petra Rust, Cem Ekmekcioglu
    International Journal of Environmental Research and Public Health.2023; 20(7): 5400.     CrossRef
  • The role of serum vitamin 25(OH)D concentration in the Covid-19 pandemic in children
    Chrysoula Kosmeri, Foteini Balomenou, Dimitrios Rallis, Maria Baltogianni, Vasileios Giapros
    British Journal of Nutrition.2023; 130(3): 417.     CrossRef
  • Vitamin D metabolism parameters in hospitalized COVID-19 patients
    A. A. Mikhailova, K. A. Golovatyuk, D. I. Lagutina, A. T. Chernikova, E. Yu. Vasilieva, E. S. Bykova, T.  L. Karonova
    Translational Medicine.2023; 10(2): 69.     CrossRef
  • Characteristics, comorbidities and laboratory measures associated with disease severity and poor prognosis in young and elderly patients with COVID-19 admitted to medical wards in Emilia-Romagna region, Italy: a multicentre retrospective study
    Sirio Fiorino, Andrea Carusi, Alessandro Zappi, Fabio Tateo, Luca Peruzzo, Melissa Zanardi, Francesco Savelli, Giulia Di Marzio, Silvia Cesaretti, Francesca Dazzani, Raffaella Francesconi , Paolo Leandri , Gianfranco Tortorici , Susanna Vicari , Dora Melu
    Italian Journal of Medicine.2023;[Epub]     CrossRef
  • Six years’ experience and trends of serum 25-hydroxy vitamin D concentration and the effect of vitamin D3 consumption on these trends
    László Horváth, Sara Mirani, Michael Magdy Fahmy Girgis, Szilvia Rácz, Ildikó Bácskay, Harjit Pal Bhattoa, Béla E. Tóth
    Frontiers in Pharmacology.2023;[Epub]     CrossRef
  • Neuroimmunological Effect of Vitamin D on Neuropsychiatric Long COVID Syndrome: A Review
    Ting-Bin Chen, Ching-Mao Chang, Cheng-Chia Yang, I-Ju Tsai, Cheng-Yu Wei, Hao-Wen Yang, Chun-Pai Yang
    Nutrients.2023; 15(17): 3802.     CrossRef
  • Effects of environmental parameters and their interactions on the spreading of SARS-CoV-2 in North Italy under different social restrictions. A new approach based on multivariate analysis
    Fabio Tateo, Sirio Fiorino, Luca Peruzzo, Maddalena Zippi, Dario De Biase, Federico Lari, Dora Melucci
    Environmental Research.2022; 210: 112921.     CrossRef
  • The Relation between Vitamin D Level and Lung Clearance Index in Cystic Fibrosis—A Pilot Study
    Mihaela Dediu, Ioana Mihaiela Ciuca, Liviu Laurentiu Pop, Daniela Iacob
    Children.2022; 9(3): 329.     CrossRef
  • Effect of Cholecalciferol Supplementation on the Clinical Features and Inflammatory Markers in Hospitalized COVID-19 Patients: A Randomized, Open-Label, Single-Center Study
    Tatiana L. Karonova, Ksenia A. Golovatyuk, Igor V. Kudryavtsev, Alena T. Chernikova, Arina A. Mikhaylova, Arthur D. Aquino, Daria I. Lagutina, Ekaterina K. Zaikova, Olga V. Kalinina, Alexey S. Golovkin, William B. Grant, Evgeny V. Shlyakhto
    Nutrients.2022; 14(13): 2602.     CrossRef
  • Vitamin D Endocrine System and COVID-19: Treatment with Calcifediol
    Jose Manuel Quesada-Gomez, José Lopez-Miranda, Marta Entrenas-Castillo, Antonio Casado-Díaz, Xavier Nogues y Solans, José Luis Mansur, Roger Bouillon
    Nutrients.2022; 14(13): 2716.     CrossRef
  • Impaired Vitamin D Metabolism in Hospitalized COVID-19 Patients
    Alexandra Povaliaeva, Viktor Bogdanov, Ekaterina Pigarova, Larisa Dzeranova, Nino Katamadze, Natalya Malysheva, Vitaliy Ioutsi, Larisa Nikankina, Liudmila Rozhinskaya, Natalia Mokrysheva
    Pharmaceuticals.2022; 15(8): 906.     CrossRef
  • Vitamin D and COVID-19. Two years of research
    Andrey P. Fisenko, Svetlana G. Makarova, Dmitry S. Yasakov, Irina Yu. Pronina, Oksana A. Ereshko, Irina G. Gordeeva, Albina A. Galimova, Tamara R. Chumbadze, Evgeny Е. Emelyashenkov, Ayina M. Lebedeva
    Russian Pediatric Journal.2022; 25(3): 199.     CrossRef
  • Vitamin D as the essential immunonutrient – the evidence base update: A review
    Svetlana G. Makarova, Evgeny E. Emelyashenkov, Dmitry S. Yasakov, Irina Yu. Pronina, Oksana A. Ereshko, Irina G. Gordeeva, Albina A. Galimova, Tamara R. Chumbadze, Ayina M. Lebedeva
    Pediatrics. Consilium Medicum.2022; (2): 133.     CrossRef
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    Sonja H Brunvoll, Anders B Nygaard, Merete Ellingjord-Dale, Petter Holland, Mette Stausland Istre, Karl Trygve Kalleberg, Camilla L Søraas, Kirsten B Holven, Stine M Ulven, Anette Hjartåker, Trond Haider, Fridtjof Lund-Johansen, John Arne Dahl, Haakon E M
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    Shariq Qayyum, Radomir M. Slominski, Chander Raman, Andrzej T. Slominski
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    Frontiers in Immunology.2022;[Epub]     CrossRef
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    Current Drug Metabolism.2022; 23(8): 630.     CrossRef
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Data Profile
The Korea National Health and Nutrition Examination Survey data linked Cause of Death data
Sungha Yun, Kyungwon Oh
Epidemiol Health. 2022;44:e2022021.   Published online February 9, 2022
DOI: https://doi.org/10.4178/epih.e2022021
  • 9,462 View
  • 555 Download
  • 7 Citations
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
The Korea National Health and Nutrition Examination Survey (KNHANES) is a national health survey that is conducted annually to assess the health and and health-related behaviors of Korean population. To utilize KNHANES data to studies of mortality risk factors, the Korea Disease Control and Prevention Agency (KDCA) constructed a database linking KNHANES data to cause-of-death statistics in Statistics Korea, made available to researchers since 2020. The KNHANES data were linked to the Cause of Death Statistics based on resident registration numbers for subjects aged 19 years or older who agreed to link the data. The linkage rate between 2007-2015 National Health and Nutrition Examination Survey and 2007-2019 Cause of Death Statistics was 97.1%. In the linked dataset, the total death rate was 6.6%, of which neoplasms accounted for the highest death rate (32.1%), followed by circulatory system disease (22.7%) and respiratory system disease (11.5%). The linked dataset was made available through the Research Data Center of the KDCA after a review of the research proposal, and will be made available after periodical updates.
Summary
Korean summary
1. 국민건강영양조사 자료가 사망 위험요인 규명 연구에 활용되도록 통계청의 사망원인통계와 연계자료 구축함 2. 2007~2015년 국민건강영양조사와 2007~2019년 사망원인통계의 연계율은 97.1%이었음 3. 국민건강영양조사-사망원인통계 연계자료는 2020년부터 연구자에게 질병관리청 내 학술연구자료처리실를 통해 제공되고 있음
Key Message
1. To utilize the Korea National Health and Nutrition Examination Survey (KNHANES) data to studies of mortality risk factors, the data were linked to the Cause of Death Statistics in the Statistics Korea. 2. The linkage rate between the 2007-2015 KNHANES and the 2007-2019 Cause of Death Statistics was 97.1%. 3. The Korea National Health and Nutrition Examination Survey data linked Cause of Death data have been provided to researchers through the Research Data Center in the Korea Disease Control and Prevention Agency (KDCA) since 2020.

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  • Computational method of the cardiovascular diseases classification based on a generalized nonlinear canonical decomposition of random sequences
    Igor Atamanyuk, Yuriy Kondratenko, Valerii Havrysh, Yuriy Volosyuk
    Scientific Reports.2023;[Epub]     CrossRef
  • The Association between Advanced Liver Fibrosis and Mortality Is Modified by Dietary Quality among Korean Adults: Results from the Korea National Health and Nutrition Examination Survey with Mortality Data
    Juhee Lee, Garam Jo, Dahyun Park, Hee Ju Jun, Jae Hyun Bae, Min-Jeong Shin
    Nutrients.2023; 15(6): 1501.     CrossRef
  • Association of dietary sodium intake with impaired fasting glucose in adult cancer survivors: A population-based cross-sectional study
    Kyuwoong Kim, Hamee Kim, Tae Joon Jun, Young-Hak Kim, Dong Keon Yon
    PLOS ONE.2023; 18(5): e0286346.     CrossRef
  • Fibrosis-4 Index Predicts Long-Term All-Cause, Cardiovascular and Liver-Related Mortality in the Adult Korean Population
    Young-Gyun Seo, Stergios A. Polyzos, Kyung-Hee Park, Christos S. Mantzoros
    Clinical Gastroenterology and Hepatology.2023;[Epub]     CrossRef
  • The serotype-specific prevalence of pneumococci in hospitalized pneumonia patients with COPD: a prospective, multi-center, cohort study
    Jae Yeol Kim, Jae-Woo Jung, Min-Jong Kang, Deog Kyeom Kim, Hayoung Choi, Young-Jae Cho, Seung Hun Jang, Chang-Hoon Lee, Yeon Mok Oh, Ji Sook Park
    The Korean Journal of Internal Medicine.2023; 38(5): 714.     CrossRef
  • The Korea Cohort Consortium: The Future of Pooling Cohort Studies
    Sangjun Lee, Kwang-Pil Ko, Jung Eun Lee, Inah Kim, Sun Ha Jee, Aesun Shin, Sun-Seog Kweon, Min-Ho Shin, Sangmin Park, Seungho Ryu, Sun Young Yang, Seung Ho Choi, Jeongseon Kim, Sang-Wook Yi, Daehee Kang, Keun-Young Yoo, Sue K. Park
    Journal of Preventive Medicine and Public Health.2022; 55(5): 464.     CrossRef
  • Self-perceived Weight and Mortality in Korean Adults Based on the Korea National Health and Nutrition Examination Survey Data Linked to Cause of Death Statistics
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    Journal of Obesity & Metabolic Syndrome.2022; 31(4): 313.     CrossRef
Original Articles
Trends in health behaviors over 20 years: findings from the 1998-2018 Korea National Health and Nutrition Examination Survey
Soyeon Kim, Sunhye Choi, Jihee Kim, Suyeon Park, Young-Taek Kim, Ok Park, Kyungwon Oh
Epidemiol Health. 2021;43:e2021026.   Published online April 19, 2021
DOI: https://doi.org/10.4178/epih.e2021026
  • 9,188 View
  • 339 Download
  • 14 Citations
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
This study aimed to examine the trends in health behaviors in Korean population using data from the Korea National Health and Nutrition Examination Survey (KNHANES).
METHODS
The subjects were 96,408 adults aged 19 years or older who participated in the first (1998) through seventh (2016-2018) KNHANES health interview. The prevalence of health behaviors (cigarette smoking, alcohol drinking, and physical activity) and annual percent change (APC) were estimated using SAS and the Joinpoint program.
RESULTS
The prevalence of current cigarette smoking in men decreased by 2.8%p (APC= -2.8, p< 0.001) annually over the 20-year period, and the prevalence of exposure to secondhand smoke at home substantially decreased compared to 2005 (APC= -8.8, p< 0.001). Compared to 2005, the prevalence of current alcohol drinking in women, but not men, increased (APC= 2.0, p< 0.001), and the prevalence of binge drinking decreased in men (APC= -0.7, p< 0.001) and increased in women (APC= 2.4, p< 0.001). The prevalence of aerobic physical activity decreased from 2014 in both gendersd (p< 0.001). The prevalence of healthy behaviors practice (non-smoking, alcohol abstinence, and aerobic physical activity) was down-trending (APC= -5.3, p< 0.001), especially among women (APC= -6.4, p< 0.001).
CONCLUSIONS
Over the past 20 years, smoking behaviors improved. However, drinking behavior was unchanged and physical activity indicators markedly decreased. More active programs are necessary for improving health behaviors, which are major risk factors linked to chronic diseases.
Summary
Korean summary
국민건강영양조사(1998-2018) 자료를 활용하여 지난 20년간 성인의 건강행태를 분석한 결과 흡연율과 간접흡연 노출률은 지속적으로 감소하였고, 신체활동 실천율 또한 감소하였다. 월간음주율과 폭음률의 경우 남자는 큰 변화가 없었던 반면 여자는 모두 증가하였다.
Key Message
This study aimed to examine the trends in health behaviors in Korean population using data from the 1998-2018 Korea National Health and Nutrition Examination Survey (KNHANES). Over the past 20 years, the prevalence of cigarette smoking and exposure to secondhand smoke in Korean adults consistently decreased, as well as the prevalence of physical activity. There was no considerable change in men, whereas in women, the prevalence of alcohol drinking and binge drinking both increased.

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    Jin-Kyoung Oh, Minji Han, Byungmi Kim, Eun Young Park
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    Graefe's Archive for Clinical and Experimental Ophthalmology.2023; 261(4): 1127.     CrossRef
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    Cancer Medicine.2023; 12(7): 8754.     CrossRef
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    Nursing Open.2023; 10(6): 4071.     CrossRef
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    COPD: Journal of Chronic Obstructive Pulmonary Disease.2023; 20(1): 153.     CrossRef
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    Journal of Preventive Medicine and Public Health.2023; 56(3): 248.     CrossRef
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    Biomedicines.2023; 11(8): 2212.     CrossRef
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    Clinical Hypertension.2023;[Epub]     CrossRef
  • Combinations of lifestyle behaviors and cancer risk among Korean adults
    Ngoc Minh Luu, Thi Tra Bui, Thi Phuong Thao Tran, Thi Huyen Trang Nguyen, Jin-Kyoung Oh
    Scientific Reports.2023;[Epub]     CrossRef
  • Association of Muscle Strength with Non-Alcoholic Fatty Liver Disease in Korean Adults
    Sung-Bum Lee, Yu-Jin Kwon, Dong-Hyuk Jung, Jong-Koo Kim
    International Journal of Environmental Research and Public Health.2022; 19(3): 1675.     CrossRef
  • Association of Handgrip Strength with Diabetes Mellitus in Korean Adults According to Sex
    Sung-Bum Lee, Ji-Eun Moon, Jong-Koo Kim
    Diagnostics.2022; 12(8): 1874.     CrossRef
  • Smoking trajectory and cancer risk: A population-based cohort study
    Minh Luu, Minji Han, Tra Bui, Phuong Thao Tran, Min-Kyung Lim, Jin Oh
    Tobacco Induced Diseases.2022; 20(August): 1.     CrossRef
  • Awareness of and practice toward cancer prevention recommendations: results of the Korean National Cancer Prevention Awareness and Practice Survey in 2021
    Jin-Kyoung Oh, Eunjung Park, Byungmi Kim, Yoon-Jung Choi, E Hwa Yun, Min Kyung Lim, Jeong-Soo Im, Eun Young Park
    Epidemiology and Health.2022; 44: e2022068.     CrossRef
Outbreak of carbapenem-resistant Enterobacterales at a long-term care facility in Seoul, Korea: surveillance and intervention mitigation strategies
Yoojin Park, Euncheol Son, Young June Choe, Cho Ryok Kang, Sangmi Roh, Young Ok Hwang, Sung-il Cho, Jihwan Bang
Epidemiol Health. 2023;45:e2023057.   Published online June 9, 2023
DOI: https://doi.org/10.4178/epih.e2023057
  • 1,459 View
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AbstractAbstract AbstractSummary PDF
Abstract
OBJECTIVES
Because effective decolonization options are not available, and treatment options are limited, carbapenem-resistant Enterobacterales (CRE) constitute increasingly threatening nosocomial pathogens. To prevent CRE-associated transmission and ensure patient safety, healthcare personnel and everyone in contact with CRE-infected patients must implement stringent infection control practices. This report describes a CRE outbreak, possibly related to a caregiver at a long-term care facility (LTCF), and presents a new surveillance model to improve the infection control of CRE in Seoul, Korea.
METHODS
The Seoul Metropolitan Government surveillance system identified an outbreak of CRE in an LTCF in 2022. We obtained data on the demographic characteristics and contact histories of the inpatients, medical staff, and caregivers. To isolate the inpatients and employees exposed to CRE, we used rectal swab samples and environmental sampling during the study period (May-December 2022).
RESULTS
We identified 18 cluster cases (1 caregiver and 17 inpatients) and 12 sporadic cases with CRE, and conducted a complete 197-day follow-up of all cases in the LTCF’s isolation wards.
CONCLUSIONS
This investigation demonstrated that our surveillance model and targeted intervention, based on the cooperation of the municipal government, public health center, and infection control advisory committee, effectively contained the epidemic at the LTCF. Measures to improve the compliance of all employees in LTCFs with infection control guidelines should also be adopted.
Summary
Korean summary
서울시 CRE 감시체계를 통해 2022년 한 요양병원의 집단발생을 인지하였다. 현장역학조사를 실시하여 18명의 집단발생 사례(1명 간병인, 17명 입원환자)와 12명의 산발적인 사례를 확인하였고 감염관리 컨설팅을 통해 유행을 확산을 방지하는 중재를 시행하였다.
Key Message
The Seoul Metropolitan Government surveillance system identified an outbreak of carbapenem-resistant Enterobacterales (CRE) in a long-term care facility (LTCF) in 2022. We identified 18 cluster cases (1 caregiver and 17 inpatients) and 12 sporadic cases with CRE. In the current study, we could demonstrate that our surveillance model and targeted intervention, based on the cooperation of the municipal government, public health center, and infection control advisory committee, effectively contained the epidemic at the LTCF. Measures to improve the compliance of all employees in LTCFs with infection control guidelines should also be adopted.
Systematic Reviews
Prevalence of high-risk HPV genotypes in sub-Saharan Africa according to HIV status: a 20-year systematic review
Jude Ogechukwu Okoye, Chukwudi Amaechi Ofodile, Oluwaseun Kelechi Adeleke, Okechi Obioma
Epidemiol Health. 2021;43:e2021039.   Published online May 25, 2021
DOI: https://doi.org/10.4178/epih.e2021039
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  • 316 Download
  • 14 Citations
AbstractAbstract AbstractSummary PDF
Abstract
OBJECTIVES
This review assessed the rate of high-risk human papillomavirus (HPV) infection among women living in sub-Saharan Africa. It also determined the prevalence of high-risk HPV (hrHPV) among human immunodeficiency virus (HIV) seropositive (HIV+) and seronegative (HIV-) women in sub-Saharan Africa, pre-2010 and post-2010.
METHODS
In this systematic review, Google Scholar, PubMed Central, and Embase were searched to identify cohort and case-control studies that investigated the relationship between HIV and HPV infection. The database searches yielded 17 studies published between 1999 and 2018.
RESULTS
In the general population, the prevalence of any HPV/multiple HPV infections was higher among HIV+ (53.6/22.6%) than among HIV- women (26.5/7.3%) with odds ratios of 3.22 and 3.71, respectively (95% confidence interval, 3.00 to 3.42 and 2.39 to 5.75, p< 0.001). The prevalent HPV genotypes among HIV+ and HIV- women diagnosed with invasive cervical cancer (ICC) were HPV-16/18 and HPV-45. The prevalence of HPV-16, HPV-18, and HPV-45 was lower in 1999-2010 (3.8, 1.7, and 0.8%, respectively) than in 2011-2018 (19.1, 6.0, and 3.6%, respectively). Among women diagnosed with ICC, HIV+ women had a higher prevalence of HPV-56, HPV-31, and HPV-51 (7.3, 5.3, and 3.3%, respectively) than HIV- women (1.3, 2.2, and 0.4%, p< 0.001, p= 0.050, and p= 0.013, respectively).
CONCLUSIONS
The prevalence of HPV infection, multiple HPV infections, and non-vaccine HPV types were higher among HIV+ women than among HIV- women in sub-Saharan Africa. Although HIV infection influences the distribution of HPV types, this study suggests that cervical cancer incidence in sub-Saharan Africa is primarily driven by the prevalence of vaccine hrHPVs, especially HPV-16 and HPV-18.
Summary
Key Message
Despite increasing awareness of Human papillomavirus (HPV) among women and availability of HPV vaccines, mounting evidence shows that the age-standardized incidence rate of cervical cancer is increasing in sub-Saharan Africa. This review revealed the influences of some viruses on the trends of the disease between 1999-2010 and 2011-2018.

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  • Comparison of human papillomavirus‐based cervical cancer screening strategies in Tanzania among women with and without HIV
    Crispin Kahesa, Louise T. Thomsen, Ditte S. Linde, Bariki Mchome, Johnson Katanga, Patricia Swai, Rachel Manongi, Myassa Kjaerem, Thomas Iftner, Marianne Waldstrøm, Julius Mwaiselage, Vibeke Rasch, Susanne K. Kjær
    International Journal of Cancer.2023; 152(4): 686.     CrossRef
  • Human papillomavirus testing using existing nucleic acid testing platforms to screen women for cervical cancer: implementation studies from five sub-Saharan African countries
    Jessica Joseph, Owen Demke, Lola Ameyan, Joseph Bitilinyu-Bango, Blandine Bourgoin, Mamadou Diop, Babacar Guèye, Jibrin Kama, Marvin Lubega, Bernard Madzima, Tatenda Maparo, Tasimba Mhizha, Andrew Musoke, Susan Nabadda, Twambilire Phiri, Timothy Tchereni,
    BMJ Open.2023; 13(1): e065074.     CrossRef
  • Utilizing first void urine for high-risk HPV testing for cervical cancer screening in HIV-positive women in Katete, Zambia
    Marian Kaoma, Oladapo Olayemi, Mwila Hilton Mwaba, Kapembwa Sikwewa
    BMC Women's Health.2023;[Epub]     CrossRef
  • High-risk human papillomavirus genotype distribution among women living with and at risk for HIV in Africa
    Mkunde Chachage, Ajay P. Parikh, Anifrid Mahenge, Emmanuel Bahemana, Jonathan Mnkai, Wilbert Mbuya, Ruby Mcharo, Lucas Maganga, Jaqueline Mwamwaja, Reginald Gervas, Hannah Kibuuka, Jonah Maswai, Valentine Singoei, Michael Iroezindu, Abiola Fasina, Allahna
    AIDS.2023; 37(4): 625.     CrossRef
  • The state of human papillomavirus research in Africa
    Kehinde Kazeem Kanmodi, Eyinade Adeduntan Egbedina, Jimoh Amzat, Kafayat Aminu, Lawrence Achilles Nnyanzi
    Public Health Challenges.2023;[Epub]     CrossRef
  • Measuring the impact of COVID-19 social distancing measures on sexual health behaviours and access to HIV and sexual and reproductive health services for people living with HIV in Botswana
    Samuel Ensor, Imogen Mechie, Rebecca Ryan, Aamirah Mussa, Bame Bame, Lefhela Tamuthiba, Neo Moshashane, Chelsea Morroni
    Frontiers in Global Women's Health.2023;[Epub]     CrossRef
  • Malignancy and viral infections in Sub-Saharan Africa: A review
    Mahamadou Diakite, Kathryn Shaw-Saliba, Chuen-Yen Lau
    Frontiers in Virology.2023;[Epub]     CrossRef
  • Cervicovaginal Microbiota Profiles in Precancerous Lesions and Cervical Cancer among Ethiopian Women
    Brhanu Teka, Kyoko Yoshida-Court, Ededia Firdawoke, Zewditu Chanyalew, Muluken Gizaw, Adamu Addissie, Adane Mihret, Lauren E. Colbert, Tatiana Cisneros Napravnik, Molly B. El Alam, Erica J. Lynn, Melissa Mezzari, Jhingran Anuja, Eva Johanna Kantelhardt, A
    Microorganisms.2023; 11(4): 833.     CrossRef
  • High-risk human papillomavirus genotype distribution among women living with HIV; implication for cervical cancer prevention in a resource limited setting
    Patrick Kafui Akakpo, Sebastian Ken-Amoah, Nancy Innocentia Ebu Enyan, Elizabeth Agyare, Emmanuel Salia, Ibrahim Baidoo, Leonard Derkyi-Kwarteng, Matthew Asare, George Adjei, Stephen Ayisi Addo, Dorcas Obiri-Yeboah
    Infectious Agents and Cancer.2023;[Epub]     CrossRef
  • HPV prevalence among young adult women living with and without HIV in Botswana for future HPV vaccine impact monitoring
    Nancy McClung, Anikie Mathoma, Julia W. Gargano, Naledi Gape Nyepetsi, Troy D. Querec, Juanita Onyekwuluje, Madisa Mine, Chelsea Morroni, Rebecca Luckett, Lauri E. Markowitz, Doreen Ramogola-Masire
    BMC Infectious Diseases.2022;[Epub]     CrossRef
  • Acting on the call for cervical cancer elimination: Planning tools for low- and middle- income countries to increase the coverage and effectiveness of screening and treatment
    Tara Herrick, Kerry A. Thomson, Michelle Shin, Sarah Gannon, Vivien Tsu, Silvia de Sanjosé
    BMC Health Services Research.2022;[Epub]     CrossRef
  • The preference of women living with HIV for the HPV self-sampling of urine at a rural HIV clinic in Uganda
    Agnes Nyabigambo, Roy W. Mayega, Hilbert Mendoza, Aslam Shiraz, John Doorbar, Lynn Atuyambe, Themba G. Ginindza
    Southern African Journal of Infectious Diseases.2022;[Epub]     CrossRef
  • Cervical cancer prevention and control in women living with human immunodeficiency virus
    Philip E. Castle, Mark H. Einstein, Vikrant V. Sahasrabuddhe
    CA: A Cancer Journal for Clinicians.2021; 71(6): 505.     CrossRef
  • Exogenous Vimentin Supplementation Transiently Affects Early Steps during HPV16 Pseudovirus Infection
    Sinead Carse, Dirk Lang, Arieh A. Katz, Georgia Schäfer
    Viruses.2021; 13(12): 2471.     CrossRef
The prevalence of Q fever in the Eastern Mediterranean region: a systematic review and meta-analysis
Mozhgan Ahmadinezhad, Leila Mounesan, Amin Doosti-Irani, Manijeh Yousefi Behzadi
Epidemiol Health. 2022;44:e2022097.   Published online October 28, 2022
DOI: https://doi.org/10.4178/epih.e2022097
  • 3,228 View
  • 129 Download
  • 1 Citations
AbstractAbstract PDFSupplementary Material
Abstract
OBJECTIVES
Q fever, caused by the bacterium, is a major zoonotic disease around the world. This disease is common in the Eastern Mediterranean region; therefore, we conducted the first systematic review and meta-analysis on its prevalence in humans, animals, and ticks in the Eastern Mediterranean region.
METHODS
Major Iranian and international databases were searched from 2000 to 2021. We extracted the prevalence of Q fever in blood samples from animals and milk samples from animals, ticks, and humans as the main outcome. We reported the prevalence of seropositivity and molecular positivity as point estimates and 95% confidence intervals (CIs).
RESULTS
In this review, 112 papers were identified. The overall seroprevalence of Q fever was 22.4% (95% CI, 19.8 to 25.1). The pooled prevalence of Q fever in ticks was 17.5% (95% CI, -1.3 to 36.4). The prevalence was 25.5% (95% CI, 16.1 to 34.9) in humans. The prevalence of Q fever in animal blood samples from goats, sheep, camels, cattle, cats, dogs, horses, and buffalo were 28.1%, 25.1%, 25.0%, 20.1%, 9.8%, 8.4%, 6.5%, and 6.3%, respectively. Furthermore, the prevalence of Q fever in milk samples of animals was higher in cattle (20.3%) than in sheep (20.0%), goats (16.4%), and camels (3.3%).
CONCLUSIONS
Coxiella burnetii infections are common in humans and in a wide range of animal species, but they are still not recognized in many countries in the Eastern Mediterranean region, thus presenting a significant threat to human and animal health in the region.
Summary

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  • Two Cases of Acute Q Fever Diagnosed by mNGS and Literature Review
    娇 罗
    Advances in Clinical Medicine.2023; 13(07): 12005.     CrossRef
COVID-19: Special Article
Changes in health behaviors and obesity of Korean adolescents before and during the COVID-19 pandemic: a special report using the Korea Youth Risk Behavior Survey
Chang-Mo Oh, Yangha Kim, Jieun Yang, Sunhye Choi, Kyungwon Oh
Epidemiol Health. 2023;45:e2023018.   Published online February 14, 2023
DOI: https://doi.org/10.4178/epih.e2023018
  • 3,598 View
  • 302 Download
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
This study aimed to investigate changes in health behaviors, including cigarette smoking, alcohol drinking, physical activity, dietary behaviors, and obesity, before and during the coronavirus disease 2019 (COVID-19) pandemic using the Korea Youth Risk Behavior Survey (KYRBS) database.
METHODS
KYRBS data from 2015 to 2021 were used in this study. Differences in health behaviors between before (pre-pandemic period: 2018-2019) and during (pandemic period: 2020-2021) the pandemic were examined. Differences were compared using linear regression and the chi-square test considering the complex survey design after adjusting for grade level.
RESULTS
The prevalence of current cigarette smoking and current alcohol drinking significantly decreased in both male and female students during the pandemic compared to the pre-pandemic period. However, the prevalence of obesity significantly increased in both male and female students during the same period. When examining physical activity and dietary behaviors closely related to obesity, fast food consumption increased and fruit consumption decreased during the pandemic in both male and female students, whereas no significant changes in physical activity were observed in either male or female students.
CONCLUSIONS
The deterioration of adolescent dietary behaviors and an increase in the prevalence of obesity can increase the future disease burden, and concerted efforts at the individual and national levels are needed to reduce obesity and promote healthy dietary behaviors.
Summary
Korean summary
이 연구는 한국 청소년건강행태조사자료(KYRBS)를 사용하여 코로나19 유행 전후의 우리나라 청소년들의 흡연, 음주, 신체활동, 식습관, 비만 등의 건강행태의 변화에 대하여 살펴보고자 하였다. 이 연구에서는 2015년부터 2021년까지의 청소년건강행태조사자료를 사용하여, 코로나19 유행 이전 (2018-2019년)과 코로나 유행 이후 (2020-2021년) 기간의 건강행태의 변화에 대하여 조사하였다. 학년레벨을 보정한 후, 복합표본설계를 고려하여 로지스틱 회귀분석과 카이제곱검정을 이용하여 코로나19 유행 이전 (2018-2019년)과 비교하여, 코로나 유행 이후 (2020-2021년) 기간의 건강행태의 변화가 있었는지에 대하여 확인하였다. 그 결과, 코로나19 유행 이전 (2018-2019년)과 비교하여, 코로나19 유행 기간(2020-2021년) 동안에 현재흡연율과 현재음주율이 유의하게 감소하였다. 그러나 동일한 기간 동안에 남학생과 여학생 모두에서 비만율이 유의하게 증가하였는데, 비만율과 관련된 신체활동 및 식습관에 대하여 살펴보았을 때, 신체활동에서는 유의한 변화가 없었던 반면, 남학생과 여학생 모두에서 패스트푸드 섭취는 증가하고 과일섭취가 감소한 것으로 나타났다. 따라서 코로나19 유행기간 동안 흡연율 및 음주율 등의 청소년 건강에 유익한 변화도 있었으나, 비만율도 같이 증가한 것을 확인할 수 있었다. 청소년기의 식습관의 악화 및 비만율의 증가는 미래 우리나라의 질병부담을 증가시킬 수 있기 때문에, 청소년의 비만율을 낮추고 건강한 식습관을 증진시키기 위한 개인 및 사회 차원의 노력이 필요하다.
Key Message
-The current cigarette smoking and current alcohol drinking rates significantly decreased among Korean adolescents during the pandemic period compared to the pre-pandemic period. -On the other hand, the obesity rate increased significantly especially among Korean male adolescents, which is accompanied by changes in dietary habits such as an increase in fast food intake and a decrease in fruit intake.
Original Article
Association of blood pressure measurements in sitting, supine, and standing positions with the 10-year risk of mortality in Korean adults
Inkyung Baik, Nan Hee Kim, Seong Hwan Kim, Chol Shin
Epidemiol Health. 2023;45:e2023055.   Published online June 8, 2023
DOI: https://doi.org/10.4178/epih.e2023055
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
This prospective cohort study investigated the association between blood pressure (BP) as measured in different body postures and all-cause and cardiovascular (CV) mortality risk.
METHODS
This population-based investigation included 8,901 Korean adults in 2001 and 2002. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured sequentially in the sitting, supine, and standing positions and classified into 4 categories: (1) normal, SBP <120 mmHg and DBP <80 mmHg; (2) high normal/prehypertension, SBP 120-129 mmHg and DBP <80 mmHg/SBP 130-139 mmHg or DBP 80-89 mmHg; (3) grade 1 hypertension (HTN), with SBP 140-159 mmHg or DBP 90-99 mmHg; and (4) grade 2 HTN, SBP ≥160 mmHg or DBP ≥100 mmHg. The date and cause of individual deaths were confirmed in the death record data compiled until 2013. Data were analyzed using Cox proportional hazard regression.
RESULTS
Significant associations were found between the BP categories and all-cause mortality, but only when BPs were measured in the supine position. The multivariate hazard ratios (95% confidence intervals, [CIs]) were 1.36 (95% CI, 1.06 to 1.75) and 1.59 (95% CI, 1.06 to 2.39) for grade 1 HTN and grade 2 HTN, respectively, compared with the normal category. The associations between the BP categories and CV mortality were significant regardless of body posture among participants ≥65 years, whereas they were significant for supine BP measurements only in those <65 years.
CONCLUSIONS
BP measured in the supine position predicted all-cause mortality and CV mortality better than BP measured in other postures.
Summary
Korean summary
본 역학 연구는 한국 성인 8,901명을 연구대상자로 하여 기초조사에서 세가지 자세, 즉 앉은 자세, 누운 자세, 일어선 자세에서 혈압을 측정하고, 이후 10년 동안의 사망 여부를 추적조사하여, 측정 자세에 따른 혈압과 사망 위험과의 관련성을 분석하였다. 그 결과, 누운 자세에서 측정된 고혈압(기준: 수축기 혈압이 140 mmHg 이상 혹은 이완기 혈압이 90 mmHg 이상)인 사람은 정상 혈압(기준: 수축기 혈압이 120 mmHg 미만이고 이완기 혈압이 80 mmHg 미만)인 사람에 비해 36%(1단계 고혈압) 혹은 59%(2단계 고혈압) 가량 총 사망 위험이 유의적으로 증가하는 것으로 나타났다. 이에 비해, 앉은 자세 및 일어선 자세에서 측정, 정의된 고혈압은 총 사망 위험을 증가시켰지만 유의적인 결과를 나타내지 못했다. 추후 연구에서 재확인이 필요하지만, 본 연구 결과가 시사하는 바는 앉은 자세나 일어선 자세보다 누운 자세에서 측정하는 혈압이 총 사망 위험을 더 잘 예측하므로, 고혈압 진단 외의 추가적인 활용 가능성이 있는 것으로 평가된다.
Key Message
The current epidemiological study revealed that blood pressure measured in a supine position could predict all-cause mortality and cardiovascular mortality better than blood pressure measured in a sitting or standing position. As a result, blood pressure measurements in a supine position may be useful in assessing mortality risk.
Systematic Review
Association between gallstones and the risk of biliary tract cancer: a systematic review and meta-analysis
Dan Huang, Hyundeok Joo, Nan Song, Sooyoung Cho, Woosung Kim, Aesun Shin
Epidemiol Health. 2021;43:e2021011.   Published online February 3, 2021
DOI: https://doi.org/10.4178/epih.e2021011
  • 11,557 View
  • 375 Download
  • 11 Citations
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
Biliary tract cancers (BTCs) are rare but highly fatal. Although the etiology of BTC is poorly understood, gallstones are proposed to be a major risk factor. We conducted a systematic review and meta-analysis to examine the associations between gallstone characteristics and BTC risk.
METHODS
We searched the MEDLINE, Embase, and Cochrane Central databases and systematically reviewed cohort and case-control studies published before April 9, 2018. All the included studies reported appropriate risk estimates and confidence intervals (CIs) for associations between the presence, size, number, or duration of gallstones and the risk of BTC, including gallbladder cancer (GBC), extrahepatic bile duct cancer (EBDC), and ampulla of Vater cancer (AOVC). Summary odds ratios (ORs) and their 95% CIs were calculated using a random-effects model in the meta-analysis. Subgroup analyses were conducted to inspect sources of potential heterogeneity, and the Egger test was performed to assess publication bias.
RESULTS
Seven cohort studies and 23 case-control studies in Asian, European, and American populations were included. The presence of gallstones was associated with an increased risk of BTC (OR, 4.38; 95% CI, 3.23 to 5.93; I2=91.2%), GBC (OR, 7.26; 95% CI, 4.33 to 12.18), EBDC (OR, 3.17; 95% CI, 2.24 to 4.50), and AOVC (OR, 3.28; 95% CI, 1.33 to 8.11). Gallstone size (>1 vs. <1 cm; OR, 1.88; 95% CI, 1.10 to 3.22) was significantly associated with the risk of GBC.
CONCLUSIONS
Gallstone characteristics, such as presence, size, and number, are associated with an increased risk of BTC. However, significantly high heterogeneity in the meta-analyses is a limitation of this study.
Summary
Korean summary
The prevalence of APCT-detected sacroiliitis in CD patients was higher than that in controls, but the condition was asymptomatic. The clinical significance of asymptomatic sacroiliitis in Korean CD patients remains unclear.
Key Message
본 연구에서는 체계적 문헌고찰과 메타분석법을 활용하여 여러 선행연구에서 담도계암 전반과 담석의 다양한 특성사이에 연관성이 있는지 탐구하였다. 총 30개의 문헌을 분석한 결과 담석의 존재 여부가 담도계암과 각 하위 암의 위험을 모두 높이는 것으로 나타났고, 담석의 크기가 클수록 담낭암의 위험이 높은 것으로 드러났다. 본 연구는 담석과 담도계암 전반의 연관성에 대해 체계적으로 정리한 최초의 문헌으로서 담석과 담도계암의 관계에 대한 이해의 폭을 넓히고, 추후 해당 주제로 추가 연구를 수행하는 데에 있어 기준점이 될 수 있으리라 기대한다.

Citations

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  • Habitually Skipping Breakfast Is Associated with the Risk of Gastrointestinal Cancers: Evidence from the Kailuan Cohort Study
    Tong Liu, Yiming Wang, Xiaomeng Wang, Chenan Liu, Qi Zhang, Mengmeng Song, Chunhua Song, Qingsong Zhang, Hanping Shi
    Journal of General Internal Medicine.2023; 38(11): 2527.     CrossRef
  • Rapid detection of serological biomarkers in gallbladder carcinoma using fourier transform infrared spectroscopy combined with machine learning
    Jingrui Dou, Wubulitalifu Dawuti, Jintian Li, Hui Zhao, Run Zhou, Jing Zhou, Renyong Lin, Guodong Lü
    Talanta.2023; 259: 124457.     CrossRef
  • Gallbladder Clear Cell Carcinoma: Report of a Rare Case and Literature Review
    Panayiotis Papatheodorou, Kyriakos Frantzeskou, Kyriaki Konstantinou, Elena Theophanous, Eric Bergeron
    Case Reports in Surgery.2023; 2023: 1.     CrossRef
  • Mediterranean diet and olive oil, microbiota, and obesity-related cancers. From mechanisms to prevention
    Enrique Almanza-Aguilera, Ainara Cano, Mercedes Gil-Lespinard, Nerea Burguera, Raul Zamora-Ros, Antonio Agudo, Marta Farràs
    Seminars in Cancer Biology.2023; 95: 103.     CrossRef
  • Cholecystectomy reduces the risk of cholangiocarcinoma in patients with complicated gallstones, but has negligible effect on hepatocellular carcinoma
    Hyeong Sik Ahn, Hyun Jung Kim, Tae Uk Kang, Seon Mee Park
    Journal of Gastroenterology and Hepatology.2022; 37(4): 669.     CrossRef
  • Primary spindle cell sarcoma of gallbladder
    Xin Long, Yan Chen, Wei-Xun Chen, Yu Wu, Jia Song, Jin Chen, Lei Zhang
    Medicine.2022; 101(2): e28549.     CrossRef
  • Circulating miRNA and cell-free DNA as a potential diagnostic tool in early detection of biliary tract cancer: a meta-analysis
    Aakansha Singh, Anjana Dwivedi
    Biomarkers.2022; 27(5): 399.     CrossRef
  • Immunogenetic clustering of 30 cancers
    Lisa M. James, Apostolos P. Georgopoulos
    Scientific Reports.2022;[Epub]     CrossRef
  • Risk factors for the occurrence of ampullary tumors: A case‐control study
    Piera Zaccari, Livia Archibugi, Giulio Belfiori, Enrico Nista, Giuseppe dell'Anna, Stefano Crippa, Tommaso Schepis, Matteo Tacelli, Francesca Aleotti, Maria Chiara Petrone, Alberto Mariani, Guido Costamagna, Antonio Gasbarrini, Alberto Larghi, Massimo Fal
    United European Gastroenterology Journal.2022; 10(7): 730.     CrossRef
  • Evolving Paradigms in the Systemic Treatment of Advanced Gallbladder Cancer: Updates in Year 2022
    Zishuo Ian Hu, Kian-Huat Lim
    Cancers.2022; 14(5): 1249.     CrossRef
  • Feedback Signaling between Cholangiopathies, Ductular Reaction, and Non-Alcoholic Fatty Liver Disease
    Tianhao Zhou, Debjyoti Kundu, Jonathan Robles-Linares, Vik Meadows, Keisaku Sato, Leonardo Baiocchi, Burcin Ekser, Shannon Glaser, Gianfranco Alpini, Heather Francis, Lindsey Kennedy
    Cells.2021; 10(8): 2072.     CrossRef
Original Articles
Cancer incidence among male construction workers in Korea: a standardized incidence ratio analysis, 2009-2015
Soonsu Shin, Woo-Ri Lee, Jin-Ha Yoon, Wanhyung Lee
Epidemiol Health. 2023;45:e2023060.   Published online June 19, 2023
DOI: https://doi.org/10.4178/epih.e2023060
  • 1,182 View
  • 113 Download
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
Construction workers face an elevated risk for several types of cancer. Nevertheless, there is a lack of large-scale epidemiological studies examining the risk of all cancers in construction workers. This study aimed to investigate the risk of various cancers in male construction workers using the Korean National Health Insurance Service (NHIS) database.
METHODS
We used data from the NHIS database from 2009 to 2015. Construction workers were identified using the Korean Standard Industrial Classification code. We calculated the age-standardized incidence ratios (SIRs) and 95% confidence intervals (CIs) for cancer occurrence in male construction workers compared to all male workers.
RESULTS
Compared to all male workers, the SIRs for esophageal cancer (SIR, 1.24; 95% CI, 1.07 to 1.42) and malignant neoplasms of the liver and intrahepatic bile ducts (SIR, 1.18; 95% CI, 1.13 to 1.24) were significantly higher in male construction workers. The SIRs for malignant neoplasms of the urinary tract (SIR, 1.19; 95% CI, 1.05 to 1.35) and non-Hodgkin lymphoma (SIR, 1.21; 95% CI, 1.02 to 1.43) were significantly elevated in building construction workers. The SIR for malignant neoplasms of the trachea, bronchus, and lung (SIR, 1.16; 95% CI, 1.03 to 1.29) was significantly higher in heavy and civil engineering workers.
CONCLUSIONS
Male construction workers have an increased risk for esophageal cancer, liver cancer, lung cancer, and non-Hodgkin’s cancer. Our results indicate that tailored strategies for cancer prevention should be developed for construction workers.
Summary
Korean summary
건설 노동자는 작업환경에서 수많은 유해 인자에 노출되지만, 건설 노동자에서 암의 연령 표준화 발생비를 조사한 역학 연구는 부족하다. 이번 연구에서 식도암과 간담도암의 연령 표준화 발생비는 전체 남성 근로자에 비해 남성 건설 근로자에게서 증가하였다. 이러한 결과는 건설 근로자에서 암 위험이 증가했음을 나타내며, 이 직업군에서 암 예방을 위한 추가 연구와 정책이 필요함을 의미한다.
Key Message
Despite the exposure of construction workers to numerous hazardous substances at workplace, epidemiological studies investigating the risk of all cancers in this occupational group are lacking. In this study, the age-standardized incidence ratio of esophageal cancer and hepatobiliary cancers increased in male construction workers compared to all male workers. Our results underscore the increased several cancer risks faced by male construction workers, necessitating the development of tailored strategies for cancer prevention in this occupational group.
Association of group-level segregation with cardiovascular health in older adults: an analysis of data from the Korean Social Life, Health, and Aging Project
Sung-Ha Lee, Hyeok-Hee Lee, Kiho Sung, Yoosik Youm, Hyeon Chang Kim
Epidemiol Health. 2023;45:e2023041.   Published online April 4, 2023
DOI: https://doi.org/10.4178/epih.e2023041
  • 2,364 View
  • 160 Download
AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
The adverse health effects of individual-level social isolation (e.g., perceived loneliness) have been well documented in older adults. However, little is known about the impact of collective-level social isolation on health outcomes. We sought to examine the association of group-level segregation with cardiovascular health (CVH) in older adults.
METHODS
From the prospective Korean Social Life, Health, and Aging Project database, we identified 528 community-dwelling older adults who were aged ≥60 years or were married to those aged ≥60 years. Participants who belonged to smaller social groups separate from the major social group were defined as group-level-segregated. The CVH score was calculated as the number of ideal non-dietary CVH metrics (0-6), as modified from the American Heart Association’s Life’s Simple 7. Using ordinal logistic regression models, we assessed cross-sectional and longitudinal associations between group-level segregation and CVH.
RESULTS
Of the 528 participants (mean age, 71.7 years; 60.0% female), 108 (20.5%) were segregated at baseline. In the crosssectional analysis, group-level segregation was significantly associated with lower odds of having a higher CVH score at baseline after adjusting for socio-demographic factors and cognitive function (odds ratio [OR], 0.64; 95% confidence interval [CI], 0.43 to 0.95). Among 274 participants who completed an 8-year follow-up, group-level segregation at baseline was marginally associated with lower odds of having a higher CVH score at 8 years (OR, 0.49; 95% CI, 0.24 to 1.02).
CONCLUSIONS
Group-level segregation was associated with worse CVH. These findings imply that the social network structure of a community may influence its members’ health status.
Summary
Korean summary
본 연구는 “한국인의 사회적 삶, 건강과 노화에 대한 조사”(Korean Social Life, Health and Aging Project, KSHAP)에서 측정한 한 지역 내의 사회적 연결망 자료를 이용하여 사회적 분리와 심혈관 건강 사이의 관계를 살펴보았다. 그 결과, 사회적 분리는 비만, 고혈압, 콜레스테롤, 흡연, 음주 신체적 활동 등을 종합한 ‘라이프 심플 7’ 지표와 부정적인 관련성을 보였으며, 8년 후 추적 조사에서도 이 패턴이 유지되었다. 본 연구 결과는 사회적, 집단적 분리 현상이 신체적 건강에도 악영향을 초래할 수 있음을 시사한다.
Key Message
Using the prospective Korean Social Life, Health, and Aging Project (KSHAP) database, we discovered that group-level segregation was significantly associated with worse cardiovascular health (CVH). Also, we observed a tendency for baseline group-level segregation to be linked to worse CVH after an 8-year follow-up period. These findings emphasize the significance of group-level segregation as a potential contributing factor in the health outcomes of older adults.
Changes in mental health service utilization before and during the COVID-19 pandemic: a nationwide database analysis in Korea
Kyoung Hoon Kim, Sang Min Lee, Minha Hong, Kyu-Man Han, Jong-Woo Paik
Epidemiol Health. 2023;45:e2023022.   Published online February 14, 2023
DOI: https://doi.org/10.4178/epih.e2023022
  • 2,719 View
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AbstractAbstract AbstractSummary PDFSupplementary Material
Abstract
OBJECTIVES
The present study examined the impact of the coronavirus disease 2019 (COVID-19) pandemic on mental health service utilization through a comparative analysis of nationwide data regarding inpatient care users, outpatient visits, emergency department (ED) visits, and admissions via the ED before and during the pandemic.
METHODS
Data from approximately 350,000 Koreans diagnosed with mental illness were analyzed in terms of hospitalization, outpatient visits, and ED visits between January 2018 and June 2021. An interrupted time series analysis was conducted to determine the significance of changes in mental health service utilization indicators.
RESULTS
The number of hospital admissions per patient decreased by 1.2% at the start of the pandemic and 0.7% afterward. The length of hospital stay increased by 1.8% at the outbreak of the pandemic, and then decreased by 20.2%. Although the number of outpatients increased, the number of outpatient visits per patient decreased; the number of outpatient visits for schizophrenia (3.4%) and bipolar disorder (3.5%) significantly decreased immediately post-outbreak. The number of ED visits per patient decreased both immediately post-outbreak and afterward, and ED visits for schizophrenia (19.2%), bipolar disorder (22.3%), and depression (17.4%) decreased significantly immediately post-outbreak. Admissions via the ED did not show a significant change immediately post-outbreak.
CONCLUSIONS
Mental health service utilization increased during the pandemic, but medical service use decreased overall, with a particularly significant decrease in ED utilization. As the pandemic worsened, the decline in outpatient visits became more pronounced among those with severe mental illness.
Summary
Korean summary
이 연구는 COVID-19 전후 정신질환 의료서비스 이용 변화를 분석하였다. 팬데믹 기간 중에 정신질환 의료서비스는 전반적으로 감소하였고, 특히 중증 정신질환의 외래 방문이 감소하였다. 따라서, 정신질환자의 진료 연속성을 보장하기 위한 조치가 요구된다.
Key Message
This study examined the impact of the COVID-19 pandemic on mental health service utilization. The mental health service utilization decreased overall after the outbreak of COVID-19, especially outpatient visits for severe mental illness significantly decreased. Therefore, countermeasures are needed to maintain the continuity of care.

Epidemiol Health : Epidemiology and Health