| Home | E-Submission | Sitemap | Editorial Office
top_img
The Korean Journal of Critical Care Medicine > Volume 32(4); 2017 > Article
Lim, Lee, Ha, Kang, Lee, and Moon: The Authors Reply
We appreciate your interest in our paper and are thankful for taking the time to express your opinions. We would also like to thank you for the opportunity to clarify aspects of our methodology in relation to concerns on diagnostic criteria of the study patients and further express our opinions on the issue of elderly patients’ intensive care unit (ICU) care.
As for the low proportion of sepsis, the article has a limitation. The Materials and Method section states that “The ICU patients with diagnoses associated with ICU mortality were classified into 10 subcategories. Diagnoses were sorted according to main 10th revision of the International Statistical Classification of Diseases (ICD-10) codes of the patients.” Due to large number of study patients (10,366), checking whether each patient had been diagnosed of sepsis according to strict clinical definitions was impossible, and it is possible that the patients in other disease categories would have been treated for sepsis; for example, sepsis originated from pneumonia, hepatobiliary infection, etc. For future studies, data collection by reviewing individual patient’s medical charts or well-designed prospective studies could overcome the limitation mentioned above.
The very elderly patients have high risk of death for critical illness, when compared to younger age groups [1]. The elderly patients have a higher prevalence of chronic illnesses and an age-related decrease of physical ability [2]. Age of the patients is a significant factor when deciding whether patients should undergo active or palliative treatment. The author has well pointed out that aggressive ICU care for very elderly patients could not be clinically beneficial and concurs heavy economic burdens for patients’ families.
A study in Korea showed that for the elderly, the proportion of patients who had specified “do not resuscitate” is higher than younger age groups [3]. In recent publications from JAMA, Guidet et al. [4] report the results of ICE-CUB 2 study. Patients aged 75 years or more were randomized to usual care hospitals and intervention hospital group, in which the study patients were more actively admitted to ICUs when compared to the counterparts. Paradoxically, even though admission rate was two times higher, intervention group showed no clinical benefit and in-hospital mortality was even higher.
On the other hand, many studies also support ICU care for the elderly patients. A study from the Netherlands showed that both short-term and long-term risk-adjusted mortality decreased significantly in both very elderly ICU patients and patients aged less than 80 years during the period of 2008–2014 [5]. Another study in Korea showed that ICU and in-hospital mortalities were not significantly different for very elderly critically ill patients compared to the younger patients [6]. For these reasons, setting age of 80 years as a cutoff for receiving active ICU care could create other problems such as a considerable number of very elderly patients who could be recovered by active ICU care, missing opportunity of treatment. When deciding whether patients should undergo active ICU care, the age of patients should be considered in conjunction to other important factors such as wills of the patient and family to continue intensive treatment, reversibility of the disease and underlying comorbidities.
In conclusion, we agree that medical care for very elderly patients requires different clinical approaches compared to their younger counterparts. Before ICU care of very elderly patients, physicians should carefully consider various patient-related factors in the decision of aggressive versus palliative care, for optimal results.

Conflict of Interest

No potential conflict of interest relevant to this article was reported.

References

1. Nguyen YL, Angus DC, Boumendil A, Guidet B. The challenge of admitting the very elderly to intensive care. Ann Intensive Care 2011; 1: 29.
crossref pmid pmc
2. Bagshaw SM, Webb SA, Delaney A, George C, Pilcher D, Hart GK, et al. Very old patients admitted to intensive care in Australia and New Zealand: a multi-centre cohort analysis. Crit Care 2009; 13: R45.
crossref pmid pmc
3. Moon SB, Koh Y, Hong SB, Lim CM, Huh JW. Effect of timing of do-not-resuscitate orders on the clinical outcome of critically ill patients. Korean J Crit Care Med 2016; 31: 229–35.
crossref pdf
4. Guidet B, Leblanc G, Simon T, Woimant M, Quenot JP, Ganansia O, et al. Effect of systematic intensive care unit triage on long-term mortality among critically ill elderly patients in France: a randomized clinical trial. JAMA 2017; 318: 1450–9.
crossref pmid pmc
5. Karakus A, Haas LE, Brinkman S, de Lange DW, de Keizer NF. Trends in short-term and 1-year mortality in very elderly intensive care patients in the Netherlands: a retrospective study from 2008 to 2014. Intensive Care Med 2017; 43: 1476–84.
crossref pmid pdf
6. Lee SH, Lee TW, Ju S, Yoo JW, Lee SJ, Cho YJ, et al. Outcomes of very elderly (≥ 80 years) critical-ill patients in a medical intensive care unit of a tertiary hospital in Korea. Korean J Intern Med 2017; 32: 675–81.
crossref pmid pmc pdf
TOOLS
PDF Links  PDF Links
PubReader  PubReader
ePub Link  ePub Link
Full text via DOI  Full text via DOI
Download Citation  Download Citation
CrossRef TDM  CrossRef TDM
  E-Mail
  Print
Share:      
METRICS
0
Crossref
112
View
27
Download
Related article
Editorial Office
#806, Yongseong Biztel, 109 Hangang-daero, Yongsan-gu, Seoul 04376, Korea
TEL: +82-2-2077-1533   FAX: +82-2-2077-1535   E-mail: ksccm@ksccm.org
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © The Korean Society of Critical Care Medicine. All rights reserved.                 developed in m2community
Close layer
prev next