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Original Article Six year national trend of childhood aseptic meningitis incidence in Korea, 1996-2001.
Hae Kwan Cheong, Sue Kyung Park, Moran Ki, Kwan Lee
Epidemiol Health 2008;30(2):252-262
DOI: https://doi.org/10.4178/kje.2008.30.2.252
Published online: December 31, 2008
1Department of Social and Preventive Medicine, SungkyunkwanUniversity School of Medicine, Korea. hkcheong@skku.edu
2Department of Preventive Medicine, Seoul National UniversityCollege of Medicine, Korea.
3Department of Preventive Medicine, Eulji University Schoolof Medicine, Korea.
4Department of Preventive Medicine, Dongguk UniversityCollege of Medicine, Korea.
Received: 29 October 2008   • Accepted: 12 December 2008
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BACKGROUND
AND OBJECTIVES: Aseptic meningitis is a disease of children with seasonal outbreak in summer. In spite of high morbidity, it is not notifiable without reported nationwide morbidity. The authors estimated incidence of aseptic meningitis and its descriptive characteristics and time- and space-clustering pattern. SUBJECTS AND METHODs: Cases of aseptic meningitis were extracted from National Health Insurance payment request data of National Health Insurance Corporation from January 1996 to December 2001. Cases were classified by region, institution, and hospitalization. Standardized incidence was calculated and compared by the region, month of the year whether there is any clustering.
RESULTS
Nationwide incidence of aseptic meningitis among children under 15 years old over the six year period was 3.48 per 1,000 per year. Incidence was higher in female (2.80/1,000) compared to male (4.02/1,000). Age-specific incidence was highest in 5 years old. Annual incidence was highest in 1997 (8.44/1,000) and lowest in 2000 (0.79 /1,000) with outbreak every 3 or 4 years. Outbreak was mostly confined in summer months, between May and Septe- mber. However, seasonal pattern was variable by year. Southern provinces and metropolitan areas had higher incidences and pattern was more prominent in the years with higher outbreak. Time-dependent pattern of the disease from south to north was not prominent.
DISCUSSIONS
AND CONCLUSIONS: We have calculated the nationwide incidence of the aseptic meningitis over six year period. In terms of aseptic meningitis, using National Health Insurance data for the estimation of the incidence is a plausible method for the surveillance of the disease.


Epidemiol Health : Epidemiology and Health